I've been to over 90 countries. I'll never travel somewhere new before asking these 8 questions.
What are the public toilets like?

When I first started traveling, I quickly learned that there is no one right way to use the toilet.
Many Americans take the "porcelain throne" for granted, but in some parts of the world, it's common to squat over a hole in the ground.
I've also visited countries where it's customary to pay an attendant a nominal amount for a square or two of toilet paper. In some countries' restrooms, you won't find toilet paper at all — but instead, a bidet or bucket of water to wipe yourself clean.
To prepare for any and all bathroom situations, I try to bring a roll of toilet paper and plenty of hand sanitizer on every international trip.
How will I charge my devices?

Speaking of phones, you'll want to make sure you can actually charge your devices.
Outlets are different all around the world, and I've learned the hard way that even adapters labeled as "universal" usually aren't.
A quick online search will tell you which kind of adapter you need to stay powered up. Preparing ahead is important here — although airports usually sell adapters, they tend to be more expensive than ones you can order online.
Will my credit cards work?

Many Americans are used to paying for just about anything they need with the swipe of a card — or even a phone if they use Apple Pay.
However, some countries are still largely cash-based societies. If that's the case where you are traveling, always come prepared with an ATM card — and make sure your bank account has enough cash.
Finally, keep your budget in mind. If you don't have a credit card specifically designed for travel, remember you may be hit with expensive foreign transaction fees for every purchase.